FSCN1 and metastatic malignant neoplasm in the lymph nodes: Fascin and β4-integrin expression together correlated with lymph node metastasis (P = 0.001), stage (P = 0.032) and perineural extension (P = 0.028) (Additional file 7: Table S3) while fascin and K8 expression together correlated with tumor stage (P = 0.020), differentiation (P = 0.001), lymph node metastasis (P = 0.002), recurrence (P = 0.004) (Additional file 7: Table S3).