AVP and myocardial infarction: First reports on a direct comparison of high-sensitivity troponin assays and copeptin confirm the additive effect [21], and the results of the ongoing CHOPIN trial (Copeptin Helps in the early detection Of Patients with acute myocardial INfarction), a multicenter trial of 2000 patients with chest pain in the ED, should answer many of the open questions (ClinicalTrials.gov Identifier: NCT00952744).