When IFN-γ responses against the different antigens were analysed only amongst participants that responded to ESAT-6/CFP-10fp, significant p-values were obtained for all the five rpfs (Rv0867c, Rv2389c, Rv2450c, Rv1009, Rv1884c), 11 DosR encoded antigens (Rv3129, Rv2625c, Rv1996, Rv2032, Rv3126c, Rv2631, Rv3130c, Rv2624c, Rv2007c, Rv3131, Rv3127) and two TB reactivation antigens (Rv1471, Rv3862c). The gene discussed is IFNG; the disease is tuberculosis.