Cardiac8 genes-Ras association (RalGDS/AF-6) domain family member 1(cardiac hypertrophy [58,59])-solute carrier family 22 (organic cation/carnitine transporter), member 5(primary carnitine deficiency [75])-cysteine-rich, angiogenic inducer, 61(prostate cancer [76])-tropomodulin 1-transmembrane protein 38A-eukaryotic translation initiation factor 2-alpha kinase 1-snail homolog 1 (Drosophila)(colon cancer [47])-interleukin 1 receptor antagonist(coronary artery disease [77], autoinflammatory disease [54]). This evidence concerns the gene TMEM38A and systemic primary carnitine deficiency disease.