Development7 genes-TGFB-induced factor homeobox 2-thioredoxin(Alzheimer's disease [78])-E binding protein 1-potassium inwardly-rectifying channel, subfamily J, member 1(Andersen-Tawil syndrome [79], short QT syndrome [80])-retinol dehydrogenase 12 (all-trans/9-cis/11-cis)(Leber's congenital amaurosis [81])-arginine vasopressin receptor 1A-peptidylprolyl cis/trans isomerase, NIMA-interacting 1(Alzheimer's disease [82]). The gene discussed is TXN; the disease is early-onset autosomal dominant Alzheimer disease.