Most of the NKG2D ligands examined in this study were frequently expressed among the breast tumor cohort: MIC-AB in 50% of the cases; ULBP-1 in 90%; ULBP-2 in 99%; ULBP-3 in 100%; ULBP-4 in 26%; and ULBP-5 in 90%. This evidence concerns the gene ULBP3 and breast neoplasm.