AHR and neoplasm: The anticarcinogenic properties that have been attributed to isoflavones arise in all likelihood from the concerted action that is partly the result of AhR modulation and manifests in a) cell cycle regulation, b) chemoprevention due to CYP enzyme activation, c) antiproliferative and apoptotic effects mediated by up- or downregulation of tumor suppressors or promotors, d) anti-estrogenicity that is a result of the AhR/ER interaction, and e) anti-inflammatory responses.