Within the liver parenchyma close to the lesion and peri-parasitic infiltrate, Gadd45β expression was observed in hepatocytes around the portal and central veins at day30; it markedly increased at days 90 and 180 post-infection, with staining intensities from “moderate” to “strong”; then Gadd45β expression in hepatocytes mildly decreased at days 270 and 360. Here, GADD45B is linked to infection.