IGF2 and prostate carcinoma: There is some evidence to suggest that SNPs in IGF2 are associated with longevity [31], measures of adult body size [32]–[35], grip strength [36], arm and leg strength [37], and post-exercise muscle damage [38], and in a GWAS the A allele of rs7127900 near the gene has been associated with increased risk of prostate cancer [39].