However, in other populations, the risk allele or haplotype is different or does not contain DRB1*1501 as in Sardinians where MS is associated with the DRB1*0301–DQA1*0501–DQB1*0201 and DRB1*0405–DQA1*0501–DQB1*0301 haplotypes [8], or in African–Brazilian MS patients where the strongest association was observed with DQB1*0602 rather than DRB1*1501[9]. This evidence concerns the gene HLA-DRB1 and myeloid sarcoma.