No significant differences in the levels of D-dimer (1424 ng/mL; interquartile range [IQR], 745–2536 ng/mL vs. 1533.4 ng/mL; IQR, 591–2006 ng/mL, p = 0.47), TAT (5.63 ng/L; IQR, 3.62–8.9 ng/L vs. 4.86 ng/L; IQR, 3.91–6.19 ng/L, p = 0.59), soluble CD40 ligand (0.453 ng/mL; IQR, 0.339–0.60 ng/mL vs. 0.409 ng/mL; IQR, 0.201–0.60 ng/mL, p = 0.24), and MPTF procoagulant activity (0.145 pg/mL, IQR 0.094–0.265 pg/mL, vs. 0.115 pg/mL, IQR 0.056–0.173 pg/mL, p = 0.17) were observed when patients in the SS/SD/Sβ0 thalassemia group were compared with patients in the SC/Sβ+ thalassemia group. The gene discussed is CD40LG; the disease is thalassemia.