This custom SNP array provides excellent coverage of many previously suggested and functionally important candidate genes for schizophrenia, including AKT1, CHRNA7, COMT, DAO, DAOA, DISC1, DTNBP1, ERBB4, GRM3, GSK3B, NOS1AP, NRG1, PAFAH1B1, PPP3CC, PRODH, RELN, and RGS4 [3], [4]. This evidence concerns the gene COMT and schizophrenia.