LY96 and Guillain-Barre syndrome: There were several interesting genes in our study that showed strong evidence of up-regulation, such as FOS, PTGS2, HMGB2, MMP9, LY96, TTRAP, ANXA3 and CREB1. Among them, FOS, PTGS2, HMGB2, LY96, TTRAP, ANXA3 and CREB1 have never been reported to be associated with GBS.