Among multiple genes in this 12.76 Mb region, MMP16 is a placenta-specific metalloproteinase involved in reproduction, embryonic development, and tissue remodeling; TP53INP and WDR21C are apoptosis inhibitors and RUNXT1 is involved in t(8;21) leukemia translocations [31]. The gene discussed is DCAF4L2; the disease is leukemia.