Based on this result, Kato et al. [19] quantified specific IgE against eight Malassezia species, M. dermatitis, M. furfur, M. globosa, M. obtusa, M. pachydermatitis, M. slooffiae, M. sympodialis, and M. restricta, in sera from patients with AD by enzyme-linked immunosorbent assay (ELISA). This evidence concerns the gene IGHE and Alzheimer disease.