MGMT and glioblastoma: For patients with glioblastoma multiforme (GBM), treatment planning currently takes into account radiographic imaging, which documents volume and location of disease [1], and in some cases mutational analysis [2], methylation status of genomic DNA with particular emphasis on the DNA repair gene for methyl guanidine methyl transferase (MGMT [3]) and gene expression patterns of the tumour, which allows the broad categorization of tumours that are histologically similar into molecular subtypes [4].