CRP and rheumatoid arthritis: Early disease staging in RA according to American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) criteria is in addition to the enumeration of involved small and large joints based mostly on blood tests measuring the erythrocyte sedimentation rate (ESR) and levels of C-reactive protein (CRP), rheumatoid factor (RF), and anti-citrullinated protein antibodies (ACPAs) [2].