In ovalbumin sensitized rats, production of IFN-γ by CD8+ T cells suppressed eosinophilia, and in human eosinophils, IFN-γ has also been found to enhance cytokine- (GM-CSF, IL-5) induced degranulation and superoxide anion production [112,113]. Here, IFNG is linked to Increased total eosinophil count.