MYC and acute myeloid leukemia: In addition, the Ahi-1 locus was also the target of provirus insertional mutagenesis in 14% of the c-myc-induced murine T cell leukemia (Figure 1) [39], 5% of the Moloney MuLV-induced rat thymomas [38], 11% of the Hoxa9/Meis1-induced murine acute myeloid leukemia [40] and in acute myeloid leukemias arising in Nf1 heterozygous mice [41].