AHI1 and chronic myelogenous leukemia, BCR-ABL1 positive: Ahi-1/AHI-1 transcript levels are normally down-regulated during both early murine and human hematopoietic cell differentiation and are highly deregulated in certain human leukemic cells, including leukemic stem cells from patients with chronic myeloid leukemia (CML) and leukemic Sezary cells in cutaneous T-cell lymphoma (CTCL) [17, 18].