AHI1 and primary cutaneous T-cell non-Hodgkin lymphoma: Ahi-1/AHI-1 transcript levels are normally down-regulated during both early murine and human hematopoietic cell differentiation and are highly deregulated in certain human leukemic cells, including leukemic stem cells from patients with chronic myeloid leukemia (CML) and leukemic Sezary cells in cutaneous T-cell lymphoma (CTCL) [17, 18].