It requires three criteria for definition: firstly, normalization of the previously elevated serum tumor markers (alpha fetoprotein (AFP) and beta human chorionic gonadotropins (B-HCG)); secondly, an increase in tumor size during and after chemotherapy given for NSGCT; and thirdly, the absence of any NSGCT component other than mature teratoma (MT) when the tumor is resected. Here, AFP is linked to neoplasm.