PRTN3 and Hematuria: Twenty four hours after administration of anti-PR3 IgG (n = 18 mice), disease control-IgG (n = 5 mice), or IgG from healthy controls (n = 3 mice), seven (39%) of the experimental mice that received anti-PR3 IgG had developed hematuria, whereas there was no hematuria in disease or healthy control animals (0%) (p<0.01).