In the present study, we showed that the levels of HDL-C, LDL-C, ApoAI and ApoB were higher in subjects with hyperlipidemia than in subjects with normolipidemia besides serum TC and TG levels, whereas the ratio of ApoAI to ApoB was lower in subjects with hyperlipidemia than in subjects with normolipidemia. This evidence concerns the gene APOA1 and hyperlipidemia.