The only result directly present in our study was that the ACAT-1 rs1044925 SNP influenced the HDL-C and ApoAI levels in the male with hyperlipidemia, which suggests that the ACAT-1 rs1044925 SNP might influence the cellular cholesterol efflux in the male hyperlipidemic subjects. This evidence concerns the gene APOA1 and hyperlipidemia.