IFIH1 and type 1 diabetes mellitus: Using logistic regression analysis, the most strongly associated marker in IFIH1 was identified as SNP rs1990760, which encodes an alanine to threonine amino acid change at codon 946, with an odds ratio for association with T1D of 1.16 (5%–95% confidence interval, 1.11–1.22) for the major allele [65].