Follow-up analysis by Straub et al. on 262 Irish schizophrenic pedigrees identified a second gene, MRDS1/OFCC1 (encoding orofacial cleft 1 candidate 1) gene, located on 6p24.3, as a potentially novel candidate gene for schizophrenia [8], [9]. Here, OFCC1 is linked to schizophrenia.