Over all, no case of severe SIR with multiorgan failure and coagulopathy, but significant increases in body temperature, mean arterial blood pressure, and concomitantly increased serum levels of adrenaline, nor adrenaline or C-reactive protein (CRP) have been reported shortly after RF ablation [53, 54, 133, 134]. The gene discussed is CRP; the disease is blood coagulation disease.