Recently, this NSCLC subclassification has been shown to reflect also specific epidemiological as well as biological behaviors, which can be epitomized in a higher incidence in never-smokers and in women of the adenocarcinomatous subtype [4-7] and in its higher sensitivity to EGFR tyrosine kinase inhibitors [8]. Here, EGFR is linked to non-small cell lung carcinoma.