KRAS and lung carcinoma: Importantly, we and others have shown that there is a clear specificity for the nature of inflammation in lung cancer promotion, because induction of asthma-like (Th2 type) airway inflammation using weekly exposure to ovalbumin (OVA) aerosol in the same K-ras mutant mouse model [14] or in the urethane-induced lung cancer mouse model [15] did not result in a significant difference in lung surface tumor number.