There are a number of genes of potential interest within 2p14 region that are involved in innate immune response, particularly in endocytosis process, including CLEC4F, CD207, ATP6V1B1, PPP3R1, KIAA1048, ANXA4 and AAK1. These results may help guide further studies on leprosy. This evidence concerns the gene ANXA4 and leprosy.