STIM1 and Kaposi's sarcoma: Our findings expand the genetic and clinical spectra of SLC29A3 disorders and illustrate how WES could rapidly expand the clinical boundaries of known genetic defects, as previously illustrated by the discovery of STIM1 deficiency in a kindred with Kaposi sarcoma (KS), which revealed both the first genetic etiology of KS and a new phenotype of STIM1 deficiency [10].