APOE and Alzheimer disease: As compared with controls, AD cases were older (79 vs. 72 years old), included more women (65% vs. 53%), had a lower education level (elementary school: 50 vs. 10 years), more with the history of type 2 DM (18% vs. 13%), fewer with the history of hypertension (39% vs. 53%) or hyperlipidemia (18% vs. 30%), and more were ApoE ε4 carriers (40% vs. 14%, Table 1).