Infection of mice with S. mansoni showed a significant increase in serum levels of ALT (P < 0.01, P < 0.001) with a significant decrease in both albumin (P < 0.01) 18 weeks PI, and hepatic GSH (P < 0.001) 10 and 18 weeks PI in comparison with the uninfected untreated group. This evidence concerns the gene GPT and infection.