Since CXCL4/PF4 and CXCL10/IP10 represent the main CXCR3 ligands found during platelet degranulation and thus any hemorrhage and deep in reactive/wounded stromal compartment respectively, we examined functions of these two CXCR3 chemokines on prostate carcinoma cell functioning. The gene discussed is PF4; the disease is prostate carcinoma.