Looking at the CXCR3 splicing isoform expression, in contrast to RWPE-1 cells, in which CXCR3B was basically the only splice variant, both CXCR3A and CXCR3B were expressed at near equivalent levels in the two invasive and metastatic prostate cancer cell lines, DU-145 and PC-3, but not in the LNCaP cells (Figure 3B and 3C). The gene discussed is CXCR3; the disease is Familial prostate cancer.