Since there is no increase of cAMP amount after CXCL4/PF4 or CXCL10/IP10 treatment in the prostate cancer cell lines, m-calpain activities remained at same levels compared to the untreated cells (Figure 5E), suggesting that inhibition of cell migration via the CXCR3B pathway was not active in prostate cancer cells. This evidence concerns the gene CAPN2 and prostate carcinoma.