AKT1 and neoplasm: Combination of laser microdissection with kinome and protein arrays to detect phosphorylation status of many kinases involved in angiogenic signaling, for example, VEGFR2, ERK, and Akt, would furthermore broaden the options to get a clearer view on the molecular basis of tumor vascular heterogeneity [41]; yet at present this is unfeasible due to the limited amount of tissue yielded by laser microdissection.