mRNA of microdissected tumor vasculature identified by light microscopy in haematoxylin-stained biopsies, hence representing lumen-containing vasculature, showed a ~20–60 fold enrichment in endothelial marker genes CD31, VE-cadherin, vWF, and EphrinB2, compared to mRNA isolated from a tumor biopsy as a whole (Figure 4). Here, CDH5 is linked to neoplasm.