On the opposite, EphB4, FGFR1, Tie2, Alk5, TNFR2, and the adhesion molecules VCAM-1 and ICAM-1 were more frequently detected and at higher levels in normal kidney endothelium as compared to tumor endothelium from intermediate and large tumors. The gene discussed is TNFRSF1B; the disease is neoplasm.