Mutant mice with deletions in some members of the integrin family as well as downstream associates of integrins, such as focal adhesion kinase (FAK) and integrin-linked kinase (Ilk) also show cortical migration defects with deficiencies in basal lamina integrity with features that resemble human cobblestone lissencephaly [30]–[37]. This evidence concerns the gene ILK and cobblestone lissencephaly.