However, these limitations are likely not considerable because previous data have suggested that the sensitivity and specificity for the H. pylori detection method used in the present study were both more than 95% in gastric cancer patients [45] and, in contrast to what is found in Western populations, CagA seroprevalence has been reported to be greater than 95% in infected Koreans [46]. Here, S100A8 is linked to gastric cancer.