The identification of PPP3CB, and one of its inhibitors, calcineurin homologous protein (CHP) [43], is of particular interest as PPP3CB/NFAT signaling is implicated in a wide range of biological responses relevant to asthma including lymphocyte activation, as well as neuronal and muscle development [43], [44], [45]. The gene discussed is PPP3CB; the disease is asthma.