A large cluster of genes upregulated in DM are involved in T cell (IL2RB, CD2, TRAC, CD3D, CTLA4), cytotoxic/NK cell (NKG7), macrophage (CD68), and dendritic cell (CD83) function (green bar, Figs. 1A and Fig. S2), which is consistent with previous observations regarding T cell and macrophage infiltration in DM skin [21]. This evidence concerns the gene CTLA4 and dermatomyositis.