There was no significant difference in CD16 expression on CD14++ monocytes in early RA patients stratified according to gender (p = 0.437, Fig. 4A), smoking status (current smoker vs. non-smoker p = 0.258, Fig. 4C), the presence of autoantibodies (CCP pos vs. neg p = 0.082, RF pos vs. neg p = 0.610, Fig. 4D and Fig. 4E respectively), or the presence or absence of hand or foot erosions at presentation (p = 0.327, Fig. 4H and p = 0.70, Fig. 4I respectively). Here, CD14 is linked to rheumatoid arthritis.