Likewise, we observed no relationship between rs129679860 IL28B genetic polymorphisms and virological responses to pegIFN-α 2a plus Rbv in our patients with CHC G3, as has been previously reported in both G3 monoinfected and HCV/HIV-coinfected patients [27]–[29], although the existing data on this issue are not entirely homogeneous [30]. This evidence concerns the gene IFNL3 and cryohydrocytosis.