MSH2 and endometrium neoplasm: Analysis of mononucleotide BAT25, BAT26 and CAT25 markers [10] showed instability of all of them and immunohistochemistry of MLH1/PMS2 and MSH2/MSH6 proteins indicated the loss of MSH2/MSH6 expression in the endometrial tumor; direct sequencing of the MSH2 gene on ABI 3500 (Applied Biosytems) genetic analyzer revealed the same c.2388delT mutation (p.Thr796ThrfxX15) in exon 14 (Figure 2).