Subjects with both the IL4 CC and IL6 GG genotypes showed the highest mean eGFR (79.1 ml/min/1.73 m2) and lowest CKD prevalence (0.0%), while subjects carrying both the IL4 TT and IL6 CC genotypes showed the lowest mean eGFR (73.4 ml/min/1.73 m2) and highest CKD prevalence (17.9%). The gene discussed is IL4; the disease is chronic kidney disease.