EGFR and cancer: A number of EGFR inhibitors including the monoclonal antibodies cetuximab (Erbitux) and panitumumab (Vectoibix) and small molecule tyrosine kinase inhibitors gefitinib (Iressa) and erlotinib (Tarceva) have shown potential in the treatment of several types of human cancers (reviewed by Karar and Maity, [33]).