NPPB and acute kidney injury: However, the more intense diuretic treatment was not associated with a larger decline in body weight or natriuretic peptide levels during the hospitalization (weight loss AKI: -3.0 kg ± 5.4 kg versus non-AKI: -4.3 kg ± 5.1 kg; P = 0.48; BNP change AKI: -57% (-31% to -77%) versus -48% (-8% to -70%), P = 0.38).