CRP and rheumatoid arthritis: At baseline, patients in the MAD phase of the study had had a diagnosis of RA for a median of 8 years (IQR = 4 to 11, range = 0.6 to 30), with a median baseline CRP of 1.7 mg/dL (IQR = 1.3 to 3, range = 0.9 to 4.6), median erythrocyte sedimentation rate of 31 mm/hr (IQR = 24 to 64, range = 11 to 97), median SJC of 9 (IQR = 9 to 16, range = 5 to 45), median TJC of 17 (IQR = 11 to 31, range = 5 to 65) and a median DAS28-CRP score of 5.6 (IQR = 4.9 to 5.9, range = 3.9 to 7.9).