LGALS3 and benign thyroid gland neoplasm: On a single gene basis, FNAB of histologically proven malignant thyroid tumours (n=18) showed significantly lower mRNA expression levels for TFF3 and HGD1 and significantly higher mRNA levels for ADM3 and LGALS3 compared with FNAB of benign thyroid tumours (n=93) (Table 2A).