As shown in Table 4, a significant association was observed between the TERT rs2736100 polymorphism and adenocarcinoma susceptibility in all genetic models (GG versus TT: OR = 1.85, 95% CI: 1.72, 1.98; GT versus TT: OR = 1.44, 95% CI: 1.31, 1.59; dominant model-TG + GG versus TT: OR = 1.56, 95% CI 1.42, 1.71; recessive model-GG versus TT + TG: OR = 1.50, 95% CI: 1.41, 1.60; additive model-2GG + TG versus 2TT + TG: OR = 1.36, 95% CI: 1.31, 1.41). This evidence concerns the gene TERT and adenocarcinoma.