CRP and malaria: For illustration, when a hypothetical decision rule for severe malaria was created solely based on a CRP cut-off level of ≥ 155 mg/L, 10 of 62 (or 16.1%) evaluable patients with non-falciparum disease and 26 of 116 (or 22.4%) evaluable patients with uncomplicated P. falciparum would have been falsely diagnosed as having severe malaria.