Taking this fact into consideration Colak et al. had conducted a study investigating the effects of low- (1 microg; LDT) and standard- (250 microg; SDT) dose ACTH stimulation tests on adrenal cortex functions in patients with Behcet's disease; 18 patients with BD and 15 controls were recruited to this study. This evidence concerns the gene POMC and Behcet disease.