IFNA2 and cutaneous melanoma: Study investigators compared two different schedules (induction 10 MU SC 5 days weekly for 4 weeks followed by maintenance 10 MU SC thrice weekly for either 12 or 24 months) of IFN-α2b to observation for patients with high risk cutaneous melanoma (T4N0M0/TxN1-2M0) with no evidence of distant metastasis or had undergone surgery for regional lymph node metastases.