In the ANCHOR (Anti-VEGF Antibody for the Treatment of Predominantly Classic Choroidal Neovascularization in AMD) trial, patients with “predominantly classic” angiographic leakage patterns were randomized to receive either 24 monthly intravitreal injections of ranibizumab (either 0.3 mg or 0.5 mg) or photodynamic therapy with verteporfin [79]. Here, VEGFA is linked to age-related macular degeneration.