A similar finding was reported by Meier et al. (2007) in neuroblastoma cell lines where invasive cells lines (IGR-N91, SH-SY5Y) had high expression levels of CXCR4, whereas a non-invasive neuroblastoma cell line (IGR NB8) expressed low levels of the CXCR4 gene [26]. This evidence concerns the gene CXCR4 and neuroblastoma.